I have been having similar issues since my GM LNF 2.0 Tune in April. Engine losing turbo (max PSI of 5-6) intermittently. The first trip back service blamed it on an improper O-ring. That worked for a couple of months, then I had the same issue, sometimes accompanied by rough idling when starting the vehicle. Codes P0236 and sometimes code P0106, same as before. The last visit service blamed it on a bad clamp. It happened again within a week, same codes. From this thread it looks like I should order the DDMWerks T bolt clamps.
I was also getting 21 PSI consistently with the LNF 2.0 tune. Now I get mostly 18 PSI, very rarely 19-20. Could that be attributed entirely to temperature/humidity? We did have a hot summer here in Austin, dry and a near record of over 100 degree days. It has cooled down recently.