I have been there numerous times myself and will go every chance I get. I usually go on one of the bikes, but last time I took my sky. I found it much more enjoyable and easier on all the senses in the car, but I like my chances of avoidance and survival better on my bikes (I know that sounds crazy but most experienced riders will understand what I mean lol). If you stick to your skill level, the other guy is all you have to worry about. Unfortunately there are a lot of idiots there and I have had very many close calls come up due to some of them. As Elff said, motorcycles are usually the ones in the wrong in my experience, and many times its a fellow sportbiker driving well above his skill level. Of course, I have seen many cruisers that just dont need to come close to the dragon lol
If you go, take your time the first few times and just enjoy the road. Don't try to drive aggressively until you have a good knowledge and memory of the tail. If you stick to that and keep an eye open for the idiots, you will be fine and have an enjoyable trip! Oh and DONT SIGHT SEE while on the tail! go hiking if you wanna do that lmao